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Showing posts from September, 2025

Chronic pain: Medication decisions

Chronic pain can limit quality of life and lead to serious health problems. Finding treatment is important — as is balancing pain relief with your safety. Prescription Medication For Sale Chronic pain is a serious health condition that can lead to complications beyond physical symptoms. People with chronic pain may experience depression, anxiety and trouble sleeping. Chronic pain is pain that is long lasting. It can affect every aspect of life — from relationships to finances. Chronic pain makes it harder to keep up with work, tasks at home and social gatherings. Some research suggests that the worse the pain, the more serious the effects on day-to-day life. For these reasons, finding effective treatment for chronic pain is important. But the process is complex and personal. What works for one person's chronic low back pain may not bring relief for another person's osteoarthritis. There are a number of reasons for this. The cause of the chronic pain, a person's biology and ...

IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS

  INDICATION JOURNAVX is indicated for the treatment of moderate-to-severe acute pain in adults. IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS Concomitant use of JOURNAVX with strong CYP3A inhibitors is contraindicated. WARNINGS AND PRECAUTIONS Increased Risk of Adverse Reactions With Concomitant Use With Strong and Moderate CYP3A Inhibitors:   Strong and moderate CYP3A inhibitors increase suzetrigine and its active metabolite exposures, which may cause adverse reactions with JOURNAVX. Risk of Drug Interactions With Certain CYP3A Substrates:  Suzetrigine is an inducer of CYP3A. If JOURNAVX is used concomitantly with sensitive CYP3A substrates or CYP3A substrates where minimal concentration changes may lead to loss of efficacy, refer to the Prescribing Information for the CYP3A substrates for dosing instructions. Dosage adjustment of the concomitant CYP3A substrates may be required when initiating or discontinuing JOURNAVX. Risk of Drug Interactions With Certain Hormonal ...